构建中包含Cre重组酶的编码区域,由小鼠绒毛蛋白1基因的12.4kb片段驱动,以及金属硫蛋白的polyadenylation序列,这个转基因构建被注入了C57BL/6J x SJL/J杂交胚胎的卵母细胞核。产生了7个系,其中Line 1000作为最初的突变株被确立(来源:J:78815)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J x SJL/J
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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