H3f3btm1Psk突变小鼠与oocyte特异性Tg(Zp3-cre)3Mrt Cre删除小鼠杂交,以剔除2-4号染色体的外显子。Southern blot、RNA的qPCR以及chromatin免疫共沉淀测序都验证了这一无义突变基因的缺失(来源:J:194593)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入,基因内删除
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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