H3f3btm1Psk突变小鼠与oocyte特异性Tg(Zp3-cre)3Mrt Cre删除小鼠杂交,以剔除2-4号染色体的外显子。Southern blot、RNA的qPCR以及chromatin免疫共沉淀测序都验证了这一无义突变基因的缺失(来源:J:194593)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count