在exon 2的上游插入了loxP位点,然后通过同源重组在exon 5下游插入了由FRT标记的pgk-EM7-neo cassette和另一个loxP位点。通过重组酶介导的重组,去除了pgk-EM7-neo cassette以及2-5号外显子。(来源:J:191046)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count