Micer质粒MHPP282m18最初被插入Nlrp1a的第10个内含子中,随后的Micer质粒MHPN379g03以顺向方式插入,距离Nlrp1c-ps大约65千碱基的端粒区域。短暂的Cre表达剪除了两个插入点间LoxP位点之间的所有序列,这删除了建库版本38中71,105,252到71,350,339的碱基对区域,同时去除了Nlrp1a的前10个外显子,以及Nlrp1b和Nlrp1c-ps的所有序列。(来源:J:191055)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因间区删除,基因内删除
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9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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