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中文
在HL^T3041的切割位点，第3041位的密码子ACT被替换成了GTT，对应的是Val。这种在Neo被通过和FLP转基因小鼠杂交后被移除的突变。预期T3041V会干扰PKD1的切割。 Western blot结果显示，突变蛋白未被切割，且表达量大约是野生型小鼠未剪切完整全长PKD1的2-3倍。(来源：J:127628)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
