Exon 3被标记了。经过改造的Exon 3有一个A到T的替换,导致第129位的苯丙氨酸被酪氨酸替代(Y129F)。要去除野生型的Exon 3并表达这个修改过的Exon 3,需要Cre介导的重组。(来源:J:193938)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Single point
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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