设计了一种靶向载体,它在exon 1的上游插入了一个loxP位点,并在exon 1下游包含一个loxP引导的诺卡因抗性(neo)基因座。通过Cre介导的重组,去除了neo基因座,留下了exon区域被敲除。(来源:J:101977, J:211733)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count