从第2个到第10个外显子之后的所有编码外显子都被替换了为诺卡因抗性基因座。 Western blot分析证实了大脑中没有蛋白质表达(来源:J:178947)
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All coding exons following exon 1 (exons 2-10) were replaced with a neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:178947)