从第3号外显子到第8号外显子被替换为相应的野生型序列,带有C端的FLAG标签(6Y-FLAG),一个FRT引导的neo cassette,一个loxP位点,以及六种免疫受体酪氨酸激活基序(ITAM)被替换为苯丙氨酸的序列,后面跟着C端的Myc标签(6F-Myc)。通过Cre介导的重组,6Y-FLAG标签和neo cassette被去除,而6F-Myc标签保持不变。(来源:J:192915)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
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1
4
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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