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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
H2-Oa/Brd2
Tg(otx2-lacZ)F5pImat
Alias:
Brd2
tg
Brd2
F5placZ
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基础信息
表型特征
文献报道
F5placZ构建包含了福库鱼otx2基因的-29至-18千碱基的5'上游区域,与福库鱼otx2启动子、lacZ基因和SV40polyA信号相连。在F5p中,转录本插入会导致H2-Oa和Brd2基因39.9千碱基的缺失(从第三个到倒数第二个外显子位置)。(引用文献:J:188139, J:193089)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5467632
CD-1
--
Insertion, Intergenic deletion
--
1
--
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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