Tg(APOE-FGF23*R176Q)#Ack

This transgene consists of the human APOE promoter with exon 1 and part of exon 2 and the human FGF23 cDNA with the R176Q mutation tagged with a myc epitope followed by the APOE poly(A) and hepatic control region. The APOE promoter drives expression of FGF23 in the liver. Two lines were established however, the pound symbol (#) is used because the line is not specified and lines are pooled. (J:93981)