一段2.5千碱基对的exon 3序列,以及部分intron 3,以及包含exon 5、intron 5和exon 6的5.2千碱基对片段,被克隆到了目标载体pKO(Lexicon)的XhoI和SalI酶切位点。PGK启动子驱动的诺卡因磷酸转移酶cDNA(用于阳性选择)和白喉毒素A中国亚种的cDNA(用于阴性选择),被克隆到了载体的AscI和RsrII位点。这段信息来自文献(J:177612)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入,基因内删除
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部