Exon 4被替换为一个构建,包含以下组件:loxP位点、exon 4、IRES、GFP、loxP、neo cassette和另一个loxP位点。通过Cre介导的重组,neo cassette、exon 4以及GFP基因被去除了(来源:J:157076)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count