这个转基因靶向的位点包含一个内含子接受器,周围是puro序列,CAG启动子,一个floxed终止子,FRT引导的终止子,来自耐盐细菌纳塔诺玛斯pharaonis的halorhodopsin,经过N端信号肽和C端内质网出口序列的改造,这些与增强黄绿色荧光蛋白(eNpHR2-EYFP)成一个框内融合,以及木鼠肝炎病毒的后转录调控元件(WPRE,用于提高mRNA的稳定性)。(来源:J:190172)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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