一段包含胸腺嘧啶激酶和新霉素抗性基因(cDNAs)以及一个loxP位点的筛选载体被插入到2号和3号外显子之间,再在3号和4号外显子间插入了另一个loxP位点。随后,Cre介导的重组去除了3号外显子和neo cassette(来源:J:189609)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部