插入了Velocigene cassette ZEN-Ub1导致了染色体2(Genome Build37)上181336169-181367617位置之间31449bp的缺失,随后的Cre表达去除掉了含诺瓦克林选择标记的 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count