在第一段外显子(1)的起始密码子(CUG)和第三段外显子(3)的终止密码子(TAA)之间的序列被替换为人源序列。通过Flp介导的重组,移除了插入到内含子2中的含floxed neo cassette的元件,从而产生了人源化Myc(参考文献J:189677)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入,基因内删除
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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