从12到36号外显子被替换为一个包含人类cDNA、连接序列、雌激素受体(ERT或ERtm)突变的雌激素结合域、polyadenylation序列和floxed neo cassette的构建。这种预测的融合蛋白功能依赖于他莫昔芬治疗。(来源:J:189329)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count