Dnah11^b2b1775Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to C substitution at the +2 position after coding nucleotide 6489 of the cDNA (c.6489+2T>C, NM_010060) in intron 39. This changes splice donor site G-GT to G-GC (which is assumed to be less efficient). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Dnah11b2b1775Clo, and may be present in stocks carrying this mutation.