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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gt(ROSA)26Sor
tm12(CD2*)Rsky
Alias:
CD2
stopFL
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基础信息
表型特征
文献报道
通过同源重组,将一个splice接受器位点、一个带有neo-stop cassette的敲除子和人类CD2基因的信号缺失的剪切缺失版本插入到了内皮1号染色体中。(来源:J:188564)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5444669
C57BL/6
Targeted
插入
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5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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