Sftpc^{tm1(cre/ERT2,rtTA)Hap}

The terminal stop codonin exon 5 of the endogenous mouse gene was replaced with an estrogen-dependent cre cDNA (creERT2) preceded in frame by a E2A peptide sequence to interrupt translation between SPC and cre mRNAs coexpressed on a single transcript and followed by a T2A peptide sequence and rtTA. This was then followed by an Frt flanked neo selection cassette. (J:175915)