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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Dcc
Tg(H2-Kb-Jak2*V617F)1Shmd
Alias:
JAK2 V617F
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基础信息
表型特征
文献报道
这个转基因包含了携带了在H-2Kb启动子控制下的、鼠源Jak2,其中第617位的苯丙氨酸被缬氨酸替换的序列。该转基因整合到了Dcc的第12个内含子中。(来源:J:130189)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5444031
(C57BL/6 x DBA/2)F1
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插入
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1
10
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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