在exon 2的上游插入了一个loxP位点。接着在exon 4的3'端插入了一个FRT标记的neo cassette,它自身带有另一个loxP位点。通过Flp介导的重组,neo cassette被移除,导致exons 2到4都被留下了loxP标记的内含子。(来源:J:188812)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
--
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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