exon 2的编码序列被替换为人源Zap70的cDNA以及带有FRT标记的neo cassette,通过Flp介导的重组去除了neo cassette。 Western blot结果显示没有内源性蛋白表达,且检测到了人源cDNA的表达。(来源:J:188422)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count