在Foxg1编码序列的首尾插入了LoxP位点。此外,还在下游的LoxP位点3'端插入了Flpe基因,位于内源基因的3'末端。通过Flp介导的重组,邻近的含Frt的氨苄青霉素抗性筛选 cassette被去除了。当Cre介导的重组发生时,Flpe在这个位点上表达。(来源:J:188355)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
10
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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