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中文
Exon 10被替换成一个带有floxed neo cassette的替换单位，以及一个经过修改的Exon 10，其中的C到T突变导致了第301位氨基酸由Leucine变为Proline(这里为P301L)。通过Cre介导的重组，neo cassette被移除。一个35kb的同源复制片段横跨了Mapt和Kansl1在3'末端的外显子。这个复制并没有影响转录表达。(来源：J:188213)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
