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中文
在Arntl基因的2号外显子上游插入了loxP位点，接着是Frt标记的neo选择性元件，以及在4号外显子下游放置了另一个loxP位点。通过这种靶向载体在胚胎干细胞中进行了同源重组，产生了Arntl的条件性突变体。随后，通过将这些突变体与表达flp重组酶的转基因小鼠杂交，删除了neo。来源：(J:188253)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
