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中文
一个包含小鼠Klf4基因的BAC克隆通过重组修复技术被修改，使得Cre重组酶序列与一个tamoxifen诱导的雌激素受体被插入在起始的甲硫氨酸(起始密码子)位置。纯化后的构建被注入到受精卵中。建立了祖先动物，并通过与Cre响应的报告基因(ROSA-lacZ)或有lox节段的Klf4动物杂交来分析Cre活性。(参考文献: J:187932, J:188101, J:189337)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
