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中文
设计了一种靶向策略，通过在基因的第3和4外显子处插入loxP位点。首先将含loxP标记的TK-neomycin插件导入第4内含子，随后剪切掉，留下一个loxP位点。接着，同样的loxP标记的TK-neomycin插件被置于第2内含子，形成一个可剔除的药物筛选标记。Cre介导的重组移除了neo插件，使得第3和4外显子被留为loxP格式。(来源：J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
