在第3外显子上游插入了一个带有3' loxP位点的FRT引导的neo cassette,接着在第5外显子下游插入了另一个loxP位点。通过Flp介导的重组,neo cassette被移除,使得3号到5号外显子成为可剪接的。(来源:J:187800)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count