一只敲除型的转基因小鼠,其cDNA中包含了EGFP(绿色荧光蛋白)和带有FRT接头的neo cassette,这个neo cassette取代了exon 2的编码序列。随后通过Flp介导的重组,去除了neo cassette。(来源:J:187615)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count