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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Havcr1
tm1Kuch
Alias:
Tim-1
deltamucin
Kim-1
deltamucin
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基础信息
表型特征
文献报道
Exon 3被通过同源重组替换为pgk-neo cassette。 Western blot结果显示,杂合子小鼠中表达了一种缩短的蛋白质。这些缺乏O-glycosylated黏蛋白区的短蛋白出现在B细胞的表面。(来源:J:186484)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5437711
B6.Cg-Thy1a
Targeted
插入,基因内删除
--
1
--
9
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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