一个敲除的neo cassette替换了基因的第2和3个外显子。 Western blot分析证实了肝脏、白色脂肪组织和肌肉中没有蛋白质表达(来源:J:183258)
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A floxed neo cassette replaced exons 2 and 3. Western blot analusis confirmed the absence of protein expression in the liver, white adipose tissue and muscle. (J:183258)