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中文
将含有一段myristoylated Tag-RFPT改造过的Red Fluorescent Protein、cre/ERT2和FRT序列旁带Kanamycin/neomycin筛选座的靶向构建插入到小鼠Wnt11基因的保守起始ATG密码子位置，位于RP23-122D14 BAC中。随后通过短暂的Flpe重组酶表达，移除了PGK-Neo/Kan筛选座。得到的修改后的Wnt11-myrTagRFP-IRES-CE BAC转基因通过C57BL/6 x DBA杂交F1母体卵子进行微注射，建立了Founder line 28。(引用文献：J:159099, J:187213)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
