Exon 1被一个带有floxed neo cassette的启动子和额外的loxP座 flank。通过Cre介导的重组,neo cassette和Exon 1被移除。刷状膜囊泡的western blot分析证实了蛋白表达的缺失。(来源:J:186790)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count