设计了一种靶向载体,将增强型绿色荧光蛋白(EGFP)插入到第3'端的外显子3后面。下游位置插入了一条由FRT和loxP序列标记的诺卡因抗性基因 cassette (neo)。通过Cre介导的重组,去除了neo cassette。(来源:J:186832)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x 129S4/SvJae)F1
Targeted
插入
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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