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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(CMV-GFP,-BBS4)4T25Vcs
Alias:
LAP-BBS4
Bbs4-pLAP
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基础信息
表型特征
文献报道
将人类BBS4和一个LAP标签(GFP后面跟着烟草马铃薯病毒TEV蛋白酶的切割位点以及一个S标签)置于CMV立即早期(IE94)启动子的驱动下,构建了一个转染载体。产生了三条表达水平最高的转基因品系,其中4T25线最为显著(J:177990)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5432908
C57BL/6J x SJL/J
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1
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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