转基因中包含一段人类cosmid p18A4的2kb片段(称为克隆B,这里简写为p18A4.B)。Line 1352细胞含有3个转录本,它们插入内含子3,导致内含子3内产生了70kb的缺失。Western blot结果显示在恶性黑色素瘤肿瘤中存在异位表达(来源:J:11894, J:83183)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
--
插入,基因内删除
半显性
1
4
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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