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中文
通过在含有Neurog2基因的BAC中进行同源重组，构建了一个靶向载体。载体中插入了ERT2iCreERT2序列，这是一种改良的cre-ERT2（带有突变的人类雌激素受体，N端和C端串联），它插入了Neurog2基因的第2外显子，取代了整个编码序列。这个载体随后通过电穿孔法导入ES细胞进行同源重组。（来源：J:185504）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
