从人类DMD中提取的一个20kb的内含子片段,不包含在小鼠前体体节中起作用的顺式调控元件,被插入到了第三个内含子位置。随后,通过Cre介导的重组,去除了位于人类序列上游的含失活Neo cassette的片段。(来源:J:184024)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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