设计了一种靶向载体,包含一个loxP序列后面跟着frt引导的诺卡因(neo)抗性基因座,该基因座位于启动子区域和外显子1上游,以及外显子1下游的另一个loxP位点。通过Flp介导的重组,去除了neo基因座,使得外显子1成为可删除的。(来源:J:184670)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
1
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部