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中文
在exon1上游插入了loxP位点，随后是带有FRT标记的PGK-neo cassette，紧接着是第三个loxP位点位于内含子3。通过flp重组酶，对靶向的鼠进行了选择 cassette的去除，使得exons 1-3被loxP位点包裹。接着，通过cre酶切，exons 1-2被剪切掉。（来源：J:184667）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
