RMCE通过重组酶介导的 cassette exchange 替换了Gt(ROSA)26Sortm1Npa中的floxed hygro cassette,新插入了EEF1A1启动子、EGFP以及FRT标记的neo cassette。在所有检测的器官中(包括唾液腺、心脏、胰腺、肝脏、肾脏、脂肪、肌肉、大脑和睾丸)都检测到了EGFP,且在睾丸中表现出强表达。(引用:J:184312)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
BALB/cJ
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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