Lmx1a^bsd

The mutation is an intergenic deletion spanning approximately 13.48 Kb of the gene (7.89 Kb upstream and 5.36 Kb downstream of exon 3, inclusive). The mutation is predicted to cause a frameshift in the translation of the encoded protein resulting in truncation after 91 amino acids. QRT-PCR confirmed reduced transcript expression at E10.5. (J:194385)