在exon 3上游插入了loxP位点,然后在exon 3下游插入了一个带有3' loxP位点的neo cassette。 Western blot结果显示,小鼠胚胎成纤维细胞和脑组织中没有检测到蛋白质表达。(来源:J:183741)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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