将两个鼠源细菌人工染色体(BAC)转基因构建一起注射,产生了Prism 1861品系。BAC RP23-290A18包含了完整的Snap25基因,通过在Snap25的起始密码子(ATG)位置插入了mCherry。BAC RP23-172H7包含了Mobp基因的全长,它在Mobp的起始密码子(ATG)位置插入了带有HA标签的YFP。之后建立了1861代突变体。(来源:J:189629)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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