设计了一个靶向载体,包含一个由loxP位点标记的诺卡因抗性基因座、内源性核糖体进入信号(IRES)和增强黄绿色荧光蛋白(eYFP)序列。该载体被插入到内源性终止密码子下游,以及3'非翻译区(UTR)上游。通过Cre介导的重组,去除了neo基因座。(来源:J:147784)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
插入
--
1
7
77

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部