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中文
通过重组修复技术，生成了一个用于修饰含Slc26a5（prestin）基因座的BAC靶向载体。在第20号外显子的终止密码子后插入了IRES-cre/ERT2-frt-neo-frt元件。载体随后电穿孔导入TL-1 ES细胞，以培育敲入小鼠。这些小鼠与Tg(ACTFlpe)9205Dym个体杂交，以消除neo cassette。来源：(J:182720)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
