在exon 3的上游插入了lox2272位点,通过同源重组在exon 4下游插入了带有FRT标记的neo cassette和另一个lox2272位点。通过Flp介导的重组,neo cassette被去除了。 Western blot分析显示,纯合子小鼠中蛋白质表达水平与野生型相似。(来源:J:182150)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入
--
1
2
18

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部