将含有Hoxd11-IRES2-nlslacZ的磁带通过同源重组插入到YFP3.1胚胎干细胞的Gt(ROSA)26Sor位点。插入的磁带前面有一个由cre介导的剪切位点,除非经过剪切,否则会阻止Hoxd11或lacZ的转录。靶向的胚胎干细胞注射到C57BL/6J囊胚中。该遗传背景的细胞系保留在C57BL/6J背景上。(来源:J:137524)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129 and C57BL/6 and CBA and Swiss Webster
Targeted
插入
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部